Medicinal Chemistry

Biliverdin targeting TcdB-DRBD inhibits Clostridioides difficile virulence and restores gut microbiota in Mongolian gerbils (Meriones unguiculatus)

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Virtual Screening and Multistage Computational Profiling of Small-Molecule Inhibitors Targeting Clostridioides difficile Toxin B

Dirlotapide represents a rapidly repositionable anti-TcdB agent that neutralizes clinically relevant subtypes through dual RBI blockade, and validation of gut-restricted …

Runze Wang

• Sep 30, 2025 • 1 min read

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Non-antibiotic small molecule inhibitors of Clostridioides difficile toxin B and screening methods thereof

Runze Wang

• Jun 11, 2025 • 1 min read

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Application of pranlukast in preparing anti-Clostridioides difficile infection drugs

Application of biliverdin molecule in preparing drugs for treating Clostridioides difficile infection